LCN2 and acute kidney injury: Compared to mice in the AKI group, those treated with EVs alone also demonstrated a significant increase in body weight (22.29 ± 3.04 vs. 29.85 ± 1.95 g, p < 0.05) and kidney weight (0.14 ± 0.02 vs. 0.20 ± 0.02 g, p < 0.05) (Figure 1A), a significant decrease in BUN (278.48 ± 37.29 vs. 81.89 ± 34.11 mg/dL, p < 0.05) and SCr (2.39 ± 0.07 vs. 1.05 ± 0.05 mg/dL, p < 0.05) (Figure 1B), and a significant decrease in serum KIM-1 (84.19 ± 8.96 pg/mL vs. 45.18 ± 4.71, p < 0.05) and NGAL (4.14 ± 0.20 pg/mL vs. 0.64 ± 0.11, p < 0.05) (Figure 1C).