Compared to untreated controls, those in the AKI group had significant elevations of ASC and Caspase-1 in the kidney (ASC: 1.00 ± 0.56 vs. 5.80 ± 1.78 normalized expression, p < 0.05; Caspase-1: 0.29 ± 0.24 vs. 10.49 ± 2.82 normalized expression, p < 0.05). Here, CASP1 is linked to acute kidney injury.