CASP1 and acute kidney injury: Compared to the AKI group, expression of these genes was suppressed following treatment with either EVs alone (ASC: 5.80 ± 1.78 vs. 2.69 ±1.74 normalized expression, p > 0.05; Caspase-1: 10.49 ± 2.82 vs. 0.97 ± 0.29 normalized expression, p < 0.05) or pFUS alone (ASC: 5.80 ± 1.78 vs. 1.15 ± 0.30 normalized expression, p < 0.05; Caspase-1: 10.49 ± 2.82 vs. 0.60 ± 0.49 normalized expression, p < 0.05).