ACE and hypertensive disorder: A recent meta-analysis involving 391 randomized controlled trials assessing exercise and medications effects on SAP, demonstrated that in populations with hypertension, different types of exercise interventions (aerobic, resistance, combination) appear to be equally effective (SAP reduction <10 mmHg) as most antihypertensive medications (ACE inhibitors, beta-blockers, diuretics, ARB, CCB) in monotherapy [26].