EIF2AK3 and neoplasm: We found that this model assigns significant, positive coefficients for the interaction terms of macrophages with ERN1 (ERN1*Macrophages, beta coefficient = 0.0012, p < 0.023) but not EIF2AK3 (EIF2AK3*Macrophages, beta coefficient = 0.0007, p < 0.155), suggesting that ERN1 but not EIF2AK3 is predictive of CD274 gene expression within tumor-infiltrating macrophages in individual tumor types (Table 1).