TF and endothelial dysfunction: Endothelial senescence shifts the endothelium to a pro‐coagulant and pro‐inflammatory status with major TF activity, endothelial dysfunction and pro‐senescent EMP shedding,22, 23 and favours the development of a senescence‐associated secretory phenotype (SASP), mainly consisting of cytokines and metalloproteases.24