However, the AUCs, sensitivity, and specificity of circulating exosomal lncRNA-GC1 were all higher compared with those of CEA, CA72-4, and CA19-9 for distinguishing patients with GC from HDs and patients with gastric precancerous lesions (patients with CAG and patients with IM) (Figure 3B; eFigure 4A-B and eTable 2 in the Supplement). Here, CEACAM5 is linked to gastric cancer.