DLC1, IFI27L1, TP73, and PTPRN2 involve in “cell death and survival” and TBC1D24, BAIAP2, CLIP2, and SULT1C2 involve in “neurological disease.” Furthermore, “DNA methylation and transcriptional repression signaling” were the top‐ranked canonical pathways of 6 drug response–related CpGs corresponding genes, and BAIAP2 involves in “axonal guidance signaling” pathway. The gene discussed is IFI27L1; the disease is nervous system disorder.