MAPK8 and hepatocellular carcinoma: To further test the role of JNK and p38 activation on HF‐induced apoptosis, HCC cells were pre‐treated with 10 μmol/L SP600125 (JNK inhibitor) or 20 μmol/L SB202190 (p38 inhibitor) for 3 hours, followed by treatment with 40 μmol/L HF for 24 hours.