PPARA and Huntington disease: 5 GO term and KEGG Pathway with the highest correlation were selected for comparing them with the sample analysis scores (Fig. 6), and we observed a negative correlation between the PPAR signaling pathway and the sample risk value in the signaling pathway, while prion diseses, huntingtons disease, preroxisome and amyotrophic leteral sclerosis als pathway were positively correlated with sample risk.