We found that as protective factors, the low expressions of CFHR1, APOA2, IL27, FCGRT and CD1D were correlated with high risk of developing poor HCC prognosis, whereas high expressions of risk factors CTSE and NCOA6 were related to high risk of poor prognosis (Fig. 3C). The gene discussed is APOA2; the disease is hepatocellular carcinoma.