However, APCS showed quite consistent expression patterns for all SF samples in western blot data, even though MS-based proteomics revealed significantly higher fold-changes of APCS protein in the AS group than the other groups (AS/RA: 15.69, AS/gout: 4.81, AS/OA: 6.53) (Table 2). The gene discussed is APCS; the disease is rheumatoid arthritis.