When subdividing the tumours based on MGMT-methylation status, the MGMT-methylated group with a high EGR3 cell fraction had a significantly shorter survival compared to the group with a low EGR3 cell fraction: Median survival 13.77 vs. 20.07 months (HR = 1.64; 95%CI = 1.04–2.58; P = 0.03, Fig. 3E). Here, MGMT is linked to neoplasm.