EGR3 and neoplasm: Stratification of EGR1 and EGR3 mRNA data from TCGA by Verhaak subtypes25 showed that neural and proneural GBMs had slightly lower levels of EGR1 mRNA compared to classical and mesenchymal tumours, while EGR3 mRNA levels were equally expressed in all tumour subtypes (Fig. 1C).