Regarding the IBD severity scores, in UC patients we found a significant negative correlation between serum adropin levels and UCEIS (r = −0.372, P = 0.043), and Mayo (r = −0.369, P = 0.044) scores, whereas in CD patients we found a significant negative correlation between serum adropin levels and SES-CD (r = −0.514, P = 0.008), HBI (r = − 0.568, P = 0.003), and CDAI (r = −0.469, P = 0.018) scores (Table 4). The gene discussed is ENHO; the disease is inflammatory bowel disease.