Most importantly, many of the disease-relevant pathways found enriched in the TC analysis using Dataset 1 were found enriched using Dataset 3 as well; including the T1D pathway; and pathways related to immune response; interferon-α, -β and -γ signalling; antigen processing and presentation; cytokine-mediated signalling; and IL-1 and IL-4 production. This evidence concerns the gene IL4 and type 1 diabetes mellitus.