They may also explain the recent finding that the avirulent phenotype of Δmyr1 parasites during in vivo mouse infections is rescuable by coinfecting animals with both wild-type and MYR1-deficient parasites (46); parasites expressing MYR1 may induce host cells to secrete paracrine factors that suppress the transcription of inflammatory gene products that would otherwise limit Δmyr1 parasite infections. The gene discussed is MYO1B; the disease is infection.