Although many lncRNAs, such as LINC00152, LINC00355, LINC00958, and urothelial carcinoma-associated 1 (UCA1), have been reported to be closely related to the pathogenesis, progression, and chemoresistance of bladder cancer [22,23,24,25], the regulatory role of exosomal lncRNAs in bladder cancer has rarely been addressed even though lncRNAs comprise a major group of exosomal components. This evidence concerns the gene UCA1 and urinary bladder cancer.