Moreover, ILK was found to play a vital role in promoting the aggressiveness of cancer cells by regulating the level and activation of several key molecular pathways downstream of integrins, such as PKB/Akt, Extracellular Regulated Kinase (ERK) and Glycogen synthase kinase-3β (GSK3β) [29,30,31]. The gene discussed is AKT1; the disease is cancer.