Activated MM ECs modulate the expression of receptors, increasing VEGF receptor (VEGFR)-2, tyrosine-protein kinase Met (cMet, also called hepatocyte growth factor receptor), fibroblast growth factor receptor (FGFR), and Tie2/Tek density, integrins, and other adhesion molecules responsible for adhesion to the ECM components and cell motility. The gene discussed is TEK; the disease is Miyoshi myopathy.