KDR and Miyoshi myopathy: It has been demonstrated that peripheral blood-purified CD34+ VEGFR-2+ cells from MM patients exposed to VEGF-A, FGF-2, and IGF, in appropriate culture conditions, acquire a typical morphology (spindle-shaped) and change their phenotype to acquire typical EC markers such as factor VIII-related antigen (FVIII-RA), vascular endothelial-cadherin (VE-cadherin), CD34, CD31, VEGFR-2, Tie-2/Tek, and E-selectin [29].