When we correlated the log2ratio of the 1Mb window harboring the FGFR1 gene, we observed a low correlation with the tumor fraction assessed with ichorCNA (iTF) for the amplified cases, and, as expected, no correlation for non-amplified cases of the respective region was balanced (or maybe only affected by a large gain) regardless of the tumor fraction (Supplementary data Figure S6). The gene discussed is FGFR1; the disease is neoplasm.