LEPR and obesity due to melanocortin 4 receptor deficiency: To determine the combined effects of metabolic health status and the LEPR rs8179183 genotype, we subdivided the participating Korean women with obesity into four groups, as follows: MHO and the GC genotype (n = 23), MHO and the GG genotype (n = 115), MUO and the GC genotype (n = 3), and MUO and the GG genotype (n = 36).