The most frequent adverse event was anemia/hypoalbuminemia (27 patients, 75.0%), which was followed by thrombocytopenia (21 patients, 58.3%), paronychia/anorexia/diarrhea/neutropenia (15 patients, 41.7%), leukopenia/aspartate aminotransferase increase (14 patients, 38.9%), fatigue/acneiform eruption (13 patients, 36.1%), and alanine aminotransferase increase/alkaline phosphatase increase/creatinine increase (11 patients, 30.6%). This evidence concerns the gene GPT and Anorexia.