Aside from that, miR-223-3p involved in the regulation of cisplatin-resistance of pancreatic cancer [35], osteosarcoma [36] and GC [37], especially, miR-223-3p promoted cisplatin resistance of GC cells via targeting F-box and WD repeat domain containing 7 (FBXW7) [37]. The gene discussed is FBXW7; the disease is familial pancreatic carcinoma.