We found that lymphocytes isolated from non-tumor-bearing mice expressed very low to undetectable ADRB3, whereas ADRB3 expression was higher in lymphocytes (4.8-fold; Fig. 5d) and monocytes (11.4-fold; Fig. 5d) from tumor-bearing mice compared with non-tumor-bearing mice. This evidence concerns the gene ADRB3 and neoplasm.