Following the first success achieved in a child with acute lymphoblastic leukemia (ALL) after infusion of anti-CD19 CAR (CD19 CAR) T cells in April 201 2[4, 5], several research institutes worldwide have reported CD19 CAR T cell therapy to be a safe and promising treatment for patients with ALL [6, 7] . Here, CD19 is linked to acute lymphoblastic leukemia.