It was also confirmed that electro-acupuncture(EA) at Zhongwan (CV12) alleviated the cisplatin-induced anorexia in rats by reducing the levels of plasma monoamine neurotransmitters 5-hydroxytryptamine, 5-hydroxyindoleacetic acid, dopamine, and norepinephrine; as well as upregulating the expression of ghrelin and neuropeptide Y [27]. The gene discussed is NPY; the disease is Anorexia.