Decreased HSD17B6 mRNA expression was associated with increased tumor grade (Fig. 4a, data from TCGA and Fig. 5a, data from Wurmbach liver dataset) and pathological stage (Fig. 4b, data from TCGA; Fig. 5b, c, data from Wurmbach Liver and Jia liver datasets). The gene discussed is HSD17B6; the disease is neoplasm.