In addition, many studies focused on the efficiency of TCM to target angiotensin converting enzyme 2 to prevent the infection of COVID-19 like emodin from genus Rheum and Polygonum, baicalin from in Scutellaria baicalensis, nicotianamine from soybean, tetra-O-galloyl-β-D-glucose from Galla chinensis, and luteolin from Veronicalina riifolia (Yi et al. 2004; Ho et al. 2007; Deng et al. 2012; Takahashi et al. 2015; Wang et al. 2016). This evidence concerns the gene ACE2 and infection.