In a cohort comprised of 82 confirmed and 58 probable (qPCR test is negative despite other indications of COVID-19 including symptoms and epidemiology) COVID-19 cases, the positive detection rate is extremely high (98.6%) when PCR is performed in conjunction with IgM ELISA for every patient as compared to qPCR analysis alone (51.9%)30. The gene discussed is CD40LG; the disease is COVID-19.