As with the WEHI7 lines, mutation of BIM in addition to BAX and BAK1 in the p53−/− T lymphoma cells also reduced the percentage of cells that took up PI following Dex treatment, although some Bax−/−Bak1−/−Bim−/− cells did take up PI, and this was reduced by treating the cells with QVD (Figs. 3a and 4c, d). The gene discussed is BCL2L11; the disease is lymphoma.