LAMA2 and muscular dystrophy: In this context, it is of interest to note that deletion of laminin-α2 chain led to muscular dystrophy in mice, making this a novel model to study merosin (i.e., laminin-α2)-deficient congenital muscular dystrophy16 since mutations in the laminin-α2 gene leads to muscular dystrophy in humans and mice18,19.