SERPINA6 and gestational diabetes: The results of this study showed that the levels of stress hormones E and NE were all increased, and positively correlated with the level of SF and TS; the content of free cortisol in GDM patients did not change, which was consistent with Kirwan’s study, which may be due to the increase in synthetic corticosteroid-binding globulin in the liver of pregnant women, resulting in the increase of binding cortisol and the decrease in free cortisol, while the decrease in cortisol stimulated adrenocortical stimulation by negative feedback12.