Second, in a meta-analysis by Nagao M et al. [4], the researchers calculated four pooled ORs for estimation (Table 3) and concluded that nonsteroidal anti-inflammatory drug (NSAID) use was associated with a decreasing cancer risk among both peroxisome proliferator-activated receptor gamma (PPARγ) rs1801282 CC carriers (P = 0) and CG + GG carriers (P = 0.006), whereas the PPARγ rs1801282 polymorphism (CG + GG vs CC) had little influence on developing cancer among non-NSAID users (P = 0.865) or NSAID users (P = 0.658) [4]. This evidence concerns the gene PPARG and cancer.