EIF4G1 and infection: For example, rotavirus nonstructural protein 3 (NSP3) interacts with eIF4G and displaces the PABP protein from eIF4F [35]; calicivirus 3C-Like proteinase inhibits cell translation by cleavage of PABP [36]; hepatitis A virus (HAV) 3C proteinase cleaves PABP in vitro and vivo [37]; coxsackievirus B3 2Apro can cleave PABP [23]; EMCV 3C proteinase induces cleavage of PABP [30]; poliovirus 3C protease cleaves PABP and eIF4G to inhibit host cell translation [24,27]; duck hepatitis A virus (DHAV) 3C protease cleaves PABP [28]; and FMDV infection induces proteolytic of PABP [26,38].