Three colonic cancer cell lines cultured in our laboratory, namely Caco-2, HCT 116, and HT-29 as well as biobanked cDNA from LoVo, SW480, and SW620 cells were screened for the expression of IL4, IL13, IL4Ra, and IL13Ra1. IL4 transcripts were expressed at low level in Caco-2 but were only barely detectable in HCT 116, HT-29, LoVo, and SW620 and undetectable in SW480 cells. Here, IL4R is linked to malignant colon neoplasm.