CLDN2 and neoplasm: The correlation analysis of gene expression in tumor tissue showed IL13Ra1 to correlate positively with ACTA2, CCL2, CDKN1A, HIF1A, TJP1, and VEGFA and tended to correlate with BCL2 while IL13 tended to correlate positively with PTGS2 and VEGFA. Expression of IL4Ra in CRC tumors correlated positively with ACTA2, BCL2, CCL2, CDKN1A, HIF1A, TJP1, and VEGFA and tended to correlate positively with BCLxL and negatively with CLDN2 and NOS2, while IL4 tended to correlate negatively with NOS2 (Table 10).