MiR122 has previously been reported to inhibit growth of hepatocellular carcinoma cells in vitro and in vivo [22] through the inhibition of different genes, including ADAM10. MiR122 also targets the 3’UTR of c-Met and its overexpression reduces proliferation and invasion of hepatocellular carcinoma cell lines [31]. This evidence concerns the gene ADAM10 and hepatocellular carcinoma.