In addition, EZH2 was shown to promote MYC expression by inhibiting the MYC-targeting miR-494-3p, resulting in a positive feedback loop between MYC, miR-26a/b-5p, EZH2, and miR-494-3p, which ensured high MYC levels and proliferation of BL [17,42]. The gene discussed is EZH2; the disease is Burkitt lymphoma.