Both genes have a high correlation with asthma pathogenicity (>3.5 p-value (−log10)), where JAK2 and STAT3 were linked to moderate and severe asthma phenotypes and have a high number of pathogenic SNPs (8 and 24 SNPs, respectively) and related human diseases (18 and 37 diseases, respectively) (Figure 1 and Table S1). This evidence concerns the gene STAT3 and asthma.