CFTR and cystic fibrosis: Despite a number of limitations of this study, notably the absence of any data about CFTR testing (the number and kind of variants is not known, a number of CF carriers might have a CFTR-RD or bear a second CFTR variant), and the low absolute risk for a carrier to develop each condition, the results of the study, if confirmed, would challenge the status of “healthy carrier” and open a new era in personalized preventive medicine.