Yao et al13 conducted a study, in which the expressions of CXCR4 and CXCR7 in gallbladder cancer specimens from 72 patients were analysed, and found that cytoplasmic CXCR4 expression (P = .006) and CXCR7 expression (P = .035) were independent prognostic factors for survival. Here, ACKR3 is linked to gallbladder cancer.