Among those that may be infection relevant are the inhibition of lysosomal acidification and trafficking with Bafilomycin A1, via inhibition of V-ATPase74, and modulation of the ER stress and the protein unfolding response pathway by targeting the Sigma1 and Sigma2 receptor by drugs like haloperidol (Fig. 5a, Tables 1a,b). The gene discussed is TMEM97; the disease is infection.