In awake animals, norepinephrine controls arousal and attention (Aston-Jones and Cohen, 2005; Carter et al., 2010), the neuropeptides Tac2 and CRH induce states of heightened anxiety (Füzesi et al., 2016; Kormos and Gaszner, 2013; Zelikowsky et al., 2018), and the neuropeptides AgRP and NPY promote behaviors associated with hunger (Chen et al., 2019; Krashes et al., 2013). This evidence concerns the gene TAC1 and Anxiety.