It has been reported that IL-17 is involved in various autoimmune diseases, including multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematosus [[93–95], and previous studies have also indicated that high expression of IL-17 induces vascular inflammation, endothelial dysfunction, arterial hypertension, hypertension, and aortic aneurysm [96, 97]. Here, IL17A is linked to autoimmune disease.