Furthermore, the 5-year survival rate of CRC patients who had both high PD-1 and high Tim-3 expressions was 45.00%, which was significantly lower than those patients with PD-1-high and Tim-3-low, PD-1-low and Tim-3-high, and PD-1-low and Tim-3-low (72.73%, 85.71%, and 90.48%, respectively). This evidence concerns the gene HAVCR2 and colorectal carcinoma.