L1CAM and anaplastic astrocytoma: However, in 109 L1CAM positive cases (26 astrocytomas, 10 oligodendrogliomas, 18 anaplastic astrocytomas, 10 anaplastic oligodendrogliomas, and 45 glioblastomas), no one (0%) had a positive result of probe separation (red/green) (Figures 1(e) and 1(f)), indicating other mechanisms might lead to the strong expression of L1CAM in some glioma cases, rather than alteration of the RELA gene.