Among all the 109 L1CAM positive gliomas, 44 cases were IDH mutated (10 astrocytomas, 10 oligodendrogliomas, 8 anaplastic astrocytomas, 10 anaplastic oligodendrogliomas, and 6 GBMs) and 65 cases were IDH wild-type (16 astrocytomas, 10 anaplastic astrocytomas, and 39 GBMs). The gene discussed is IDH2; the disease is central nervous system cancer.