Overall, miR-223 can target several genes that are involved in cell proliferation, differentiation, viability, invasion, and death by targeting Mef2c, IGF-1R, TGFBR3, CDK2, and p53, genes that have been implicated in the pathogenesis of asthma and/or COPD. This evidence concerns the gene TGFBR3 and chronic obstructive pulmonary disease.