CD40LG and Lyme disease: More recently, Seriburi et al. demonstrated in a retrospective study of patients consulting an Infectious Diseases physician for a suspicion of Lyme borreliosis, that 50 of 182 patients (27.5%, CI95% = 21.1–34.6) had a false positive IgM immunoblot, and that 78.0% of them had received unnecessary antibiotics (Seriburi et al., 2012).