Smits and colleagues established psoriasis and atopic dermatitis models using N/TERT epidermal skin by adding Th1/Th17 (TNF-α, IL-6, IL-1α, IL-17, and IL-22) cytokines and Th2 (IL-4 and IL-13) cytokines, respectively, during the final stage of the skin maturation (Smits et al., 2017). Here, IL4 is linked to atopic eczema.