Hypomagnesemia-related hypoparathyroidism (99)  Direct effect on tyrosine kinase c-Kit of tubular cells (109); low-voltage-activated T channels blockade (110, 111)  Endoplasmic reticulum stress with calcium mobilization (112)  Immune-mediated parathyroid glands destruction; interference with CaSRs (113)  Unclear (114, 115). The gene discussed is KIT; the disease is familial primary hypomagnesemia.