Although there was no association between presence of the TERT C228T mutation and bladder tumor recurrence, by stratifying the MAF of the TERT C228T at the best cut off point, the MAF of the TERT C228T mutation (≥14%) before TURBT was significantly associated with bladder tumor recurrence (p = 0.0322) (Figure 3). The gene discussed is TERT; the disease is urinary bladder neoplasm.