Cluster1 had a beneficial anti-immune response (higher IFN-γ, TNF-α and DNA damage repair response, leukocyte fraction and lower reactive stroma and angiogenesis), despite high levels of gene modules in hepatic fibrosis, proliferation and differentiation (Fig. 1c, d, Additional file 3: Fig. S5a). Here, IFNG is linked to Hepatic fibrosis.