The inverse correlations between non-α-tocopherols and tumor necrosis factor-alpha (TNF-α) varied substantially across different glucose tolerance status, with the strongest observed in prediabetes (r = −0.33 for β-/γ-tocopherol, r = −0.37 for δ-tocopherol, p < 0.01), followed by normal glucose tolerance (NGT). This evidence concerns the gene TNF and prediabetes syndrome.