KDR and ovarian carcinoma: In comparison with 10 samples of normal ovarian surface epithelium, the mRNA levels of VEGFR2 were significantly lower in 185 cases of ovarian carcinoma (P = 1.8e − 08; Figure 6(h)), and VEGFR2 was significantly downregulated in different pathological subtypes of OC (serous, mucinous, endometrioid, and clear cell), especially in the serous type (Table 1).